GSK481
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-100131-10 mg |
| CAS # | 1622849-58-4 |
| Pricing | 10 mg, USD $170.0 |
| Biological Activity | GSK481 is a highly potent, selective, and specific receptor interacting protein 1 (RIP1) kinase inhibitor with an IC50 of 1.3 nM, which inhibits Ser166 phosphorylation in wild-type human RIP1 (IC50=2.8 nM). GSK481 also exhibits excellent translation in the U937 cellular assay with an IC50 of 10 nM[1]. |
| Purity | ≥98.0% |
| MWt | 377.39 |
| Formula | C₂₁H₁₉N₃O₄ |