Anle138b
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-101855-25 mg |
| CAS # | 882697-00-9 |
| Pricing | 25 mg, USD $240.0 |
| Biological Activity | Anle138b, an oligomeric aggregation inhibitor, blocks the formation of pathological aggregates of prion protein (PrPSc) and of α-synuclein (α-syn). Anle138b strongly inhibits oligomer accumulation, neuronal degeneration, and disease progression in vivo. Anle138b has low toxicity and an excellent oral bioavailability and blood-brain-barrier penetration. Anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology[1][2]. |
| Purity | 99.18% |
| MWt | 343.17 |
| Formula | C₁₆H₁₁BrN₂O₂ |