Astemizole
Supplier | MedChemExpress |
---|---|
Product # | HY-12532-50 mg |
CAS # | 68844-77-9 |
Pricing | 50 mg, USD $165.0 |
Synonyms | R 43512 |
MWt | 458.57 |
Formula | C₂₈H₃₁FN₄O |
Biological Activity | Astemizole (R 43512), a second-generation antihistamine drug to diminish allergic symptoms with a long duration of action, is a histamine H1-receptor antagonist, with an IC50 of 4 nM. Astemizole also shows potent hERG K+ channel blocking activity with an IC50 of 0.9 nM. Astemizole has antipruritic effects[1][2]. |
Purity | ≥98.0% |