KRAS inhibitor-9
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-137497-10 mM * 1 mL |
| CAS # | 300809-71-6 |
| Pricing | 10 mM * 1 mL, USD $165.0 |
| Biological Activity | KRAS inhibitor-9, a potent KRAS inhibitor (Kd=92 μM), blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 binds to KRAS G12D, KRAS G12C and KRAS Q61H protein with a moderate binding affinity. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS inhibitor-9 selectively inhibits the proliferation of NSCLC cells with KRAS mutation but not normal lung cells[1]. |
| Purity | 99.98% |
| MWt | 292.81 |
| Formula | C₁₃H₉ClN₂S₂ |