Metarrestin
Supplier | MedChemExpress |
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Product # | HY-120118-50 mg |
CAS # | 1443414-10-5 |
Pricing | 50 mg, USD $990.0 |
Synonyms | ML246 |
MWt | 474.6 |
Formula | C₃₁H₃₀N₄O |
Biological Activity | Metarrestin (ML246) is an orally active, first-in-class and specific perinucleolar compartment inhibitor. Metarrestin disrupts the nucleolar structure and inhibits RNA polymerase (Pol) I transcription, at least in part by interacting with the translation elongation factor eEF1A2. Metarrestin blocks metastatic development and extends survival in mouse cancer models[1][2]. |
Purity | 99.85% |