Metarrestin

Supplier MedChemExpress
Product # HY-120118-50 mg
CAS # 1443414-10-5
Pricing 50 mg, USD $990.0
Synonyms ML246
MWt 474.6
Formula C₃₁H₃₀N₄O
Biological Activity Metarrestin (ML246) is an orally active, first-in-class and specific perinucleolar compartment inhibitor. Metarrestin disrupts the nucleolar structure and inhibits RNA polymerase (Pol) I transcription, at least in part by interacting with the translation elongation factor eEF1A2. Metarrestin blocks metastatic development and extends survival in mouse cancer models[1][2].
Purity 99.85%
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