ML216
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-12342-10 mM * 1 mL |
| CAS # | 1430213-30-1 |
| Pricing | 10 mM * 1 mL, USD $73.0 |
| Synonyms | CID-49852229 |
| MWt | 383.32 |
| Formula | C₁₅H₉F₄N₅OS |
| Biological Activity | ML216 (CID-49852229) is a potent, selective and cell permeable inhibitor of the DNA unwinding activity of BLM helicase with IC50s of 2.98 μM and 0.97 μM for BLMfull-length and BLM636-1298, respectively. ML216 inhibits ssDNA-dependent ATPase activity of BLM with a Ki of 1.76 µM. Antitumor avtivity[1][2]. |
| Purity | 99.77% |