Pexidartinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-16749-2 g |
| CAS # | 1029044-16-3 |
| Pricing | 2 g, USD $1250.0 |
| Synonyms | PLX-3397 |
| MWt | 417.81 |
| Formula | C₂₀H₁₅ClF₃N₅ |
| Biological Activity | Pexidartinib (PLX-3397) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib (PLX-3397) exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib (PLX-3397) induces cell apoptosis and has anti-tumor activity[1]. |
| Purity | ≥98.0% |