GW274150
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-12119-25 mg |
| CAS # | 210354-22-6 |
| Pricing | 25 mg, USD $700.0 |
| Biological Activity | GW274150 is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50=2.19 μM; Kd=40 nM) and rat iNOS (ED50=1.15 μM). GW274150 also displays less potency for both humans or rats endothelial NOS (eNOS) and neuronal NOS (nNOS). GW274150 exerts a protective role in an acute model of lung injury inflammation[1][2]. |
| MWt | 219.3 |
| Formula | C₈H₁₇N₃O₂S |