Ponesimod

Supplier MedChemExpress
Product # HY-10569-10 mM * 1 mL
CAS # 854107-55-4
Pricing 10 mM * 1 mL, USD $145.0
Synonyms ACT-128800
MWt 460.97
Formula C₂₃H₂₅ClN₂O₄S
Biological Activity Ponesimod (ACT-128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay. Ponesimod activates S1P1-mediated signal transduction with high potency (EC50=5.7 nM). Ponesimod can protect against lymphocyte-mediated tissue inflammation[1][2][3].
Purity 99.72%
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