ML417
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-136390-10 mg |
| CAS # | 1386162-69-1 |
| Pricing | 10 mg, USD $150.0 |
| Biological Activity | ML417 is a selective and brain penetrant D3 dopamine receptor (D3R) agonist, with an EC50 of 38 nM. ML417 potently promotes D3R-mediated β-arrestin translocation, G protein mediated signaling, and pERK phosphorylation with minimal effects on other GPCR-mediated signaling. ML417 exhibits neuroprotection against toxin-induced neurodegeneration of dopaminergic neurons[1]. |
| Purity | 99.65% |
| MWt | 379.45 |
| Formula | C₂₂H₂₅N₃O₃ |