CDDO-dhTFEA
Supplier | MedChemExpress |
---|---|
Product # | HY-112671-10 mg |
CAS # | 1191265-33-4 |
Pricing | 10 mg, USD $325.0 |
Synonyms | RTA dh404 |
MWt | 574.72 |
Formula | C₃₃H₄₅F₃N₂O₃ |
Biological Activity | CDDO-dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB[1]. CDDO-dhTFEA restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats[2]. |
Purity | 99.71% |