CDDO-dhTFEA

Supplier MedChemExpress
Product # HY-112671-10 mg
CAS # 1191265-33-4
Pricing 10 mg, USD $325.0
Synonyms RTA dh404
MWt 574.72
Formula C₃₃H₄₅F₃N₂O₃
Biological Activity CDDO-dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB[1]. CDDO-dhTFEA restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats[2].
Purity 99.71%
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