Clodronate disodium tetrahydrate
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-107794-10 mM * 1 mL |
| CAS # | 88416-50-6 |
| Pricing | 10 mM * 1 mL, USD $44.0 |
| Synonyms | Disodium clodronate tetrahydrate |
| MWt | 362.93 |
| Formula | CH₁₂Cl₂Na₂O₁₀P₂ |
| Biological Activity | Clodronate disodium tetrahydrate (Disodium clodronate tetrahydrate) is first-generation bisphosphonate, with anti-osteoporotic, anti-inflammatory and analgesic effects. Clodronate disodium tetrahydrate is a selective, potent, reversible and Cl- competitive vesicular nucleotide transporter (VNUT) inhibitor, with an IC50 of 15.6 nM. Clodronate disodium tetrahydrate inhibits vesicular ATP release from neurons and reduces chronic neuropathic and inflammatory pain[1][2]. |
| Purity | ≥98.0% |