AMD 3465 hexahydrobromide
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15971-10 mM * 1 mL |
| CAS # | 185991-07-5 |
| Pricing | 10 mM * 1 mL, USD $79.0 |
| Synonyms | GENZ-644494 hexahydrobromide |
| MWt | 896.07 |
| Formula | C₂₄H₄₄Br₆N₆ |
| Biological Activity | AMD 3465 hexahydrobromide (GENZ-644494 hexahydrobromide) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM), but has no effect on CCR5-using (R5) viruses. |
| Purity | ≥98.0% |