Futibatinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-100818-10 mg |
| CAS # | 1448169-71-8 |
| Pricing | 10 mg, USD $310.0 |
| Synonyms | TAS-120 |
| MWt | 418.45 |
| Formula | C₂₂H₂₂N₆O₃ |
| Biological Activity | Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC50s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC50s (wild-type FGFR2=0.9 nM; V5651=1-3 nM; N550H=3.6 nM; E566G=2.4 nM)[1][2][3]. |
| Purity | 98.80% |