Vemurafenib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-12057-1 g |
| CAS # | 918504-65-1 |
| Pricing | 1 g, USD $696.0 |
| Synonyms | PLX4032; RG7204; RO5185426 |
| MWt | 489.92 |
| Formula | C₂₃H₁₈ClF₂N₃O₃S |
| Biological Activity | Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively[1][4]. Vemurafenib induces cell autophagy[5]. |
| Purity | 99.80% |