MK2-IN-3 hydrate
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-112457 |
| CAS # | 1186648-22-5 |
| Pricing | inquire |
| Biological Activity | MK2-IN-3 hydrate (compound 16) is an orally active, selective, and ATP-competitive MAPKAP-K2 (MK-2) inhibitor with an IC50 of 0.85 nM.MK2-IN-3 hydrate is exceptional selectivity against MK-3 (IC50=0.21 μM), MK-5 (IC50=0.081 μM), ERK2 (IC50=3.44 μM), MNK1(IC50=5.7 μM) as well as CDK2, JNK2, IKK2, MSK1, and MSK2[1]. |
| Purity | ≥99.0% |
| MWt | 358.39 |
| Formula | C₂₁H₁₈N₄O₂ |