SNIPER(ABL)-039
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-111874 |
| CAS # | 2222354-29-0 |
| Pricing | inquire |
| Biological Activity | SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 nM. IC50s are 0.54 nM, 10 nM, 12 nM, and 50 nM for ABL, cIAP1, cIAP2, XIAP, respectively[1]. |
| MWt | 1114.77 |
| Formula | C₅₄H₆₈ClN₁₁O₉S₂ |