FK706

Supplier MedChemExpress
Product # HY-19269-10 mg
CAS # 144055-55-0
Pricing 10 mg, USD $850.0
Biological Activity FK706 is a potent, slow-binding and competitive inhibitor of human neutrophil elastase with an IC50 of 83 nM and a Ki of 4.2 nM. FK706 also inhibits mouse neutrophil elastase and porcine pancreatic elastase with IC50s of 22 nM and 100 nM, respectively, and has no inhibitory activity against other serine proteinases such as human pancreatic trypsin, human pancreatic α-chymotrypsin and human leukocyte cathepsin G. FK706 has anti-inflammatory effect[1][2].
Purity 99.57%
MWt 592.54
Formula C₂₆H₃₂F₃N₄NaO₇
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