Leukadherin-1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15701-10 mM * 1 mL |
| CAS # | 344897-95-6 |
| Pricing | 10 mM * 1 mL, USD $55.0 |
| Biological Activity | Leukadherin-1, a specific agonist of the leukocyte surface integrin CD11b/CD18, increases CD11b/CD18-dependent cell adhesion to fibrinogen with an EC50 of 4 μM. Leukadherin-1 enhances leukocyte adhesion to ligands (such as ICAM-1) and vascular endothelium and thus reduces leukocyte transendothelial migration and influx to the injury sites. Leukadherin-1 suppresses innate inflammatory signaling[1][2][3]. |
| Purity | ≥98.0% |
| MWt | 421.49 |
| Formula | C₂₂H₁₅NO₄S₂ |