AS1269574

Supplier MedChemExpress
Product # HY-107535-100 mg
CAS # 330981-72-1
Pricing 100 mg, USD $600.0
Biological Activity AS1269574 is a potent, orally available GPR119 agonist, with an EC50 of 2.5 μM in HEK293 cells expressing human GPR119. AS1269574 activates TRPA1 cation channels to stimulate glucagon-like peptide-1 (GLP-1) secretion. AS1269574 specifically induces glucose-dependent insulin secretion from pancreatic β-cells only under high-glucose conditions. AS1269574 has the potential for the research of type 2 diabetes[1][2].
Purity 98.76%
MWt 308.17
Formula C₁₃H₁₄BrN₃O
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