LP-935509
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-117626-5 mg |
| CAS # | 1454555-29-3 |
| Pricing | 5 mg, USD $95.0 |
| Biological Activity | LP-935509 is a selective, ATP-competitive and brain-penetrant inhibitor of adapter protein-2 associated kinase 1 (AAK1) with an IC50 and a Ki of 3.3 nM and 0.9 nM, respectively. LP-935509 is also a potent inhibitor of BIKE (IC50=14 nM) and a modest inhibitor of GAK (IC50=320 nM). LP-935509 is highly brain-penetrant and reverses fully established pain behavior following the SNL procedure[1]. |
| Purity | 99.74% |
| MWt | 396.44 |
| Formula | C₂₀H₂₄N₆O₃ |