TAK-659 hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-100867A-5 mg |
| CAS # | 1952251-28-3 |
| Pricing | 5 mg, USD $140.0 |
| Biological Activity | TAK-659 hydrochloride is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively. TAK-659 hydrochloride induces cell death in tumor cells but not in nontumor cells, and with potential for the treatment of chronic lymphocytic leukemia (CLL)[1][2][3][4]. |
| Purity | 99.69% |
| MWt | 380.85 |
| Formula | C₁₇H₂₂ClFN₆O |