SR-4835
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-130250-100 mg |
| CAS # | 2387704-62-1 |
| Pricing | 100 mg, USD $2250.0 |
| Biological Activity | SR-4835 is a potent, highly selective and ATP competitive dual inhibitor of CDK12/CDK13 (CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM). SR-4835 acts in synergy with DNA-damaging chemotherapy and PARP inhibitors and provokes triple-negative breast cancer (TNBC) cell death[1]. |
| Purity | 98.46% |
| MWt | 499.36 |
| Formula | C₂₁H₂₀Cl₂N₁₀O |