Gefitinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-50895-1 g |
| CAS # | 184475-35-2 |
| Pricing | 1 g, USD $90.0 |
| Synonyms | ZD1839 |
| MWt | 446.9 |
| Formula | C₂₂H₂₄ClFN₄O₃ |
| Biological Activity | Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity[1][2]. |
| Purity | ≥98.0% |