Talabostat mesylate
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13233A-10 mM * 1 mL |
| CAS # | 150080-09-4 |
| Pricing | 10 mM * 1 mL, USD $145.0 |
| Synonyms | Val-boroPro mesylate; PT100 mesylate |
| MWt | 310.18 |
| Formula | C₁₀H₂₃BN₂O₆S |
| Biological Activity | Talabostat mesylate (Val-boroPro mesylate; PT100 mesylate) is an orally active and nonselective dipeptidyl peptidase IV (DPP-IV) inhibitor (IC50 < 4 nM; Ki = 0.18 nM) and the first clinical inhibitor of fibroblast activation protein (FAP) (IC50 = 560 nM), inhibits DPP8/9 (IC50 = 4/11 nM; Ki = 1.5/0.76 nM), quiescent cell proline dipeptidase (QPP) (IC50 = 310 nM), DPP2, and some other DASH family enzymes. Antineoplastic and hematopoiesis- stimulating activities[1][2][3]. |
| Purity | ≥98.0% |