Ki16425
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13285-5 mg |
| CAS # | 355025-24-0 |
| Pricing | 5 mg, USD $60.0 |
| Synonyms | Debio 0719 |
| MWt | 474.96 |
| Formula | C₂₃H₂₃ClN₂O₅S |
| Biological Activity | Ki16425 (Debio 0719) is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with Kis of 0.34 μM and 0.93 μM, respectively. Ki16425 (Debio 0719) reduces the LPA-induced activation of p42/p44 MAPK[1][2]. Ki16425 also can inhibits LPA-induced dephosphorylation of Yes-associated protein (YAP)/TAZ in HEK293A cells[3]. |
| Purity | 98.24% |