Taltobulin trifluoroacetate
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15584A-10 mM * 1 mL |
| CAS # | 228266-41-9 |
| Pricing | 10 mM * 1 mL, USD $284.0 |
| Synonyms | HTI-286 trifluoroacetate; SPA-110 trifluoroacetate |
| MWt | 587.67 |
| Formula | C₂₉H₄₄F₃N₃O₆ |
| Biological Activity | Taltobulin trifluoroacetate (HTI-286 trifluoroacetate), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin trifluoroacetate inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis[1]. |
| Purity | 99.96% |