Quarfloxin
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-14776-10 mg |
| CAS # | 865311-47-3 |
| Pricing | 10 mg, USD $600.0 |
| Synonyms | CX-3543 |
| MWt | 604.67 |
| Formula | C₃₅H₃₃FN₆O₃ |
| Biological Activity | Quarfloxin (CX-3543), a fluoroquinolone derivative with antineoplastic activity, targets and inhibits RNA pol I activity, with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA (rDNA) template[1]. |
| Purity | 99.95% |