Orantinib (SU6668)
Orantinib (TSU-68, SU6668) has greatest potency against PDGFR autophosphorylation with Ki of 8 nM in a cell-free assay, but also strongly inhibits Flk-1 and FGFR1 trans-phosphorylation, little activity against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2; does not inhibit EGFR. Phase 3.
Supplier | Selleck Chemicals |
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Product # | S1470 |
Sku # | S1470-10mM/1mL |
Pricing | 10mM/1mL, $90.00 |