SN-28049
SN-28049SN is a DNA intercalating drug that binds selectively to GC-rich DNA and shows curative activity against the Colon 38 adenocarcinoma in mice. SN 28049 has a complex action that may involve poisoning of topo IIalpha, suppression of topo I and inhibition of gene transcription from promoters with SP-1 sites. These actions may contribute to the promising experimental solid tumour anticancer activity of SN 28049.
| Supplier | BOC Sciences |
|---|---|
| Product # | 492472-30-7 |
| Pricing | Inquire |
| Cas | 492472-30-7 |
| Molecular Weight | 338.41 |
| Molecular Formula | C19H22N4O2 |
| Canonical SMILES | CC1=CC=CC2=CC3=C(C(=CN(C3=O)C)C(=O)NCCN(C)C)N=C12 |