SB-334867 free base
Supplier | MedChemExpress |
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Product # | HY-10895A-10 mg |
CAS # | 792173-99-0 |
Pricing | 10 mg, USD $144.0 |
Synonyms | SB334867A free base |
MWt | 319.32 |
Formula | C₁₇H₁₃N₅O₂ |
Biological Activity | SB-334867 free base (SB334867A free base) is an excellent, selective and blood–brain barrier permeable orexin-1 (OX1) receptor antagonist, shows selectivity over OX2 (pKb=7.4), 100-fold over 5-HT2B, 5-HT2C with pKi values of 5.4 and 5.3, respectively[1]. SB-334867 reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo[2][3]. |
Purity | 99.89% |