Dinaciclib
Dinaciclib is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM in cell-free assays, respectively. It also blocks thymidine (dThd) DNA incorporation. Dinaciclib induces apoptosis through the activation of caspases 8 and 9. Phase 3.
Supplier | Selleck Chemicals |
---|---|
Product # | S2768 |
Sku # | S2768-200mg |
Pricing | 200mg, $1670.00 |
Citations for this product:
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bioRxiv - Cancer Biology 2023Quote: ... Dinaciclib (SCH727965) was purchased from Selleck Chemicals (S2768). Dinaciclib was diluted in 20% hydroxypropyl-β-cyclodextrin (w/v ...