(1S,2S)-Bortezomib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-135396 |
| CAS # | 1132709-14-8 |
| Pricing | inquire |
| Biological Activity | (1S,2S)-Bortezomib is an enantiomer of Bortezomib. Bortezomib is a cell-permeable, reversible, and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki of 0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is an anti-cancer agent and the first therapeutic proteasome inhibitor to be used in humans[1][2][3]. |
| MWt | 384.24 |
| Formula | C₁₉H₂₅BN₄O₄ |