PIM-447 dihydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-19322B-5 mg |
| CAS # | 1820565-69-2 |
| Pricing | 5 mg, USD $370.0 |
| Synonyms | LGH447 dihydrochloride |
| MWt | 513.38 |
| Formula | C₂₄H₂₅Cl₂F₃N₄O |
| Biological Activity | PIM447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan-PIM kinase inhibitor, with Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 dihydrochloride displays dual antimyeloma and bone-protective effects. PIM447 dihydrochloride induces apoptosis[1][2]. |
| Purity | ≥98.0% |