VU 0155041 sodium salt
VU 0155041 sodium salt is a potent positive allosteric modulator at mGlu4 receptors (EC50 = 798 and 693 nM at human and rat mGlu4 receptors, respectively). VU 0155041 displays no activity for 67 G protein-coupled receptors, ion channels, and transporters, and lacks antagonist activity at NMDA receptors in striatal medium spiny neurons at a concentration of 10 μM. VU 0155041 is active in in vivo models of Parkinson's disease following i.c.v. administration.
| Supplier | BOC Sciences |
|---|---|
| Product # | 1259372-69-4 |
| Pricing | Inquire |
| Cas | 1259372-69-4 |
| Molecular Weight | 338.16 |
| Molecular Formula | C14H14Cl2NNaO3 |
| Canonical SMILES | C1CCC(C(C1)C(=O)NC2=CC(=CC(=C2)Cl)Cl)C(=O)[O-].[Na+] |