Dapivirine
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-14266-10 mM * 1 mL |
| CAS # | 244767-67-7 |
| Pricing | 10 mM * 1 mL, USD $99.0 |
| Synonyms | TMC120; R147681 |
| MWt | 329.4 |
| Formula | C₂₀H₁₉N₅ |
| Biological Activity | Dapivirine (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI). Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations[1][2]. |
| Purity | 99.94% |