Forskolin (Colforsin, CAS 66575-29-9), >99%

LC Laboratories' Product Number F-9929 - Forskolin (Colforsin), >99% - for research use only. Forskolin is a naturally occurring diterpene from the Indian plant, Coleus forskohlii, that works as an activator of adenylate cyclase resulting in an increase in the intracellular concentration of cAMP. Forskolin acts as a smooth muscle relaxant and vasodilator in a concentration-dependent manner that affects both cytoplasmic calcium levels and contractile element calcium sensitivity. Forskolin is an inhibitor of mammalian glucose transporters and of a bacterial galactose-H+ transporter, GalP. Forskolin blocks PKC-activated ERK1 and ERK2 tyrosine phosphorylation and inhibits PKC-stimulated MAPK and Raf-1 activities in mouse bone-forming cells (MC3T3-E1 osteoblasts).

• Supplier: LC Laboratories
• Product #: F-9929
• Sku #: F-9929_2g