YUM70
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-138364-5 mg |
| CAS # | 423145-35-1 |
| Pricing | 5 mg, USD $350.0 |
| Biological Activity | YUM70 is a potent and selective inhibitor of glucose-regulated protein 78 (GRP78), with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer. YUM70 also has in vivo efficacy in a pancreatic cancer xenograft model[1]. |
| Purity | ≥98.0% |
| MWt | 398.84 |
| Formula | C₂₁H₁₉ClN₂O₄ |