PS210
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-121629-25 mg |
| CAS # | 1221962-86-2 |
| Pricing | 25 mg, USD $250.0 |
| Biological Activity | PS210 is a potent and selective PDK1 activator with a Kd of 3 μM and targets the PIF-binding pocket of PDK1. PS210 is inactive against other protein kinases, including PDK1 downstream signaling components such as S6K, PKB/Akt or GSK3. In cells, the prodrug of PS210 (PS423) acts as a substrate-selective inhibitor of PDK1, inhibiting the phosphorylation and activation of S6K[1][2]. |
| Purity | 98.30% |
| MWt | 380.31 |
| Formula | C₁₉H₁₅F₃O₅ |