BDTX-189
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-136789-50 mg |
| CAS # | 2414572-47-5 |
| Pricing | 50 mg, USD $450.0 |
| Biological Activity | BDTX-189 is a potent, orally active and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, including EGFR/HER2 exon 20 insertion mutants. BDTX-189 shows KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively. Anticancer activity[1]. |
| Purity | 99.94% |
| MWt | 561.03 |
| Formula | C₂₉H₂₉ClN₆O₄ |