RWJ-56110
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-108556-1 mg |
| CAS # | 252889-88-6 |
| Pricing | 1 mg, USD $450.0 |
| Biological Activity | RWJ-56110 is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 inhibits the aggregation of human platelets induced by both SFLLRN-NH2 (IC50=0.16 μM) and thrombin (IC50=0.34 μM), quite selective relative to U46619 (HY-108566). RWJ-56110 inhibits angiogenesis and blocks the formation of new vessels in vivo. RWJ-56110 induces cell apoptosis[1][2]. |
| MWt | 790.73 |
| Formula | C₄₁H₄₃Cl₂F₂N₇O₃ |