4-methoxy-3-(3-morpholinopropoxy)-2-nitrobenzonitrile
4-methoxy-3-(3-morpholinopropoxy)-2-nitrobenzonitrile is an impurity of Gefitinib. Gefitinib is an antineoplastic drug. Gefitinib effectively inhibits all tyrosine phosphorylation sites on EGFR in both the high and low EGFR-expressing cell lines including NR6, NR6M and NR6W cell lines. The phosphorylation sites Tyr1173 and Tyr992 are less sensitive requiring higher concentrations of Gefitinib for inhibition.
| Supplier | BOC Sciences |
|---|---|
| Product # | 1006378-06-8 |
| Pricing | Inquire |
| Cas | 1006378-06-8 |
| Molecular Weight | 321.33 |
| Molecular Formula | C15H19N3O5 |
| Canonical SMILES | COC1=C(C(=C(C=C1)C#N)[N+](=O)[O-])OCCCN2CCOCC2 |