MK-4101
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-100036-25 mg |
| CAS # | 935273-79-3 |
| Pricing | 25 mg, USD $260.0 |
| Biological Activity | MK-4101 is a Smoothened (SMO) antagonist (IC50 of 1.1 µM for 293 cells ) and also a potent inhibitor of the hedgehog pathway (IC50 of 1.5 µM for mouse cells; IC50 of 1 µM for KYSE180 oesophageal cancer cells). MK-4101 has robust antitumor activity that inhibits tumor cell proliferation and induces extensive apoptosis[1]. |
| Purity | 98.31% |
| MWt | 493.47 |
| Formula | C₂₄H₂₄F₅N₅O |