S18-000003

Supplier MedChemExpress
Product # HY-119366-25 mg
CAS # 2068119-11-7
Pricing 25 mg, USD $1100.0
Biological Activity S18-000003 is a potent, selective and orally active inhibitor of retinoic acid receptor-related orphan receptor-gamma-t (RORγt), with an IC50 of <30 nM towards human RORγt in competitive binding assays. S18-000003 shows selectivity for RORγt over other ROR family members (IC50>10 μM). S18-000003 can be used for the research of psoriasis with low risk of thymic aberrations[1][2].
Purity 99.26%
MWt 518.55
Formula C₂₆H₂₅F₃N₂O₄S
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