MK-212 HCl
MK-212 is a 5HT2C-receptor agonist. A dose-dependent the effect of 5HT2C-receptor agonist MK-212 on mouse behavior was demonstrated. Intraperitoneal injection of MK-212 in high doses (0.5 and 1.0 mg/kg) increased blood level of corticosterone in mice and reduced their motor activity. In low doses of 0.1 and 0.2 mg/kg, the agonist reduced anxiety, but had no effect on motor activity. It is hypothesized that low doses of MK-212 exhibited anxiolytic activity in mice.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1582 |
| CAS # | 61655-58-1 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | MK212; MK 212; MK-212 |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C8H12Cl2N4 |
| Exact Mass | 234.0439 |
| Molecular Weight | 235.112 |
| Elemental Analysis | C, 40.87; H, 5.14; Cl, 30.16; N, 23.83 |
| IUPAC/Chemical Name | 2-chloro-6-(piperazin-1-yl)pyrazine hydrochloride |
| InChi Key | PFIZGLUIYAZQFU-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C8H11ClN4.ClH/c9-7-5-11-6-8(12-7)13-3-1-10-2-4-13;/h5-6,10H,1-4H2;1H |
| SMILES Code | ClC1=CN=CC(N2CCNCC2)=N1.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Class-2 | Depression |
| Availability | 2 Weeks |