Monomethyl auristatin E
Supplier | MedChemExpress |
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Product # | HY-15162-1 g |
CAS # | 474645-27-7 |
Pricing | 1 g, USD $3240.0 |
Synonyms | MMAE; SGD-1010 |
MWt | 717.98 |
Formula | C₃₉H₆₇N₅O₇ |
Biological Activity | Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types. |
Purity | 99.92% |