MPP+ iodide
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-W008719-10 mM * 1 mL |
| CAS # | 36913-39-0 |
| Pricing | 10 mM * 1 mL, USD $220.0 |
| Biological Activity | MPP+ iodide, a toxic metabolite of the neurotoxin MPTP, causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ iodide is taken up by the dopamine transporter into dopaminergic neurons where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high affinity substrate for the serotonin transporter (SERT)[1][2]. |
| Purity | ≥98.0% |
| MWt | 297.14 |
| Formula | C₁₂H₁₂IN |