Iptacopan
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-127105-10 mg |
| CAS # | 1644670-37-0 |
| Pricing | 10 mg, USD $680.0 |
| Synonyms | LNP023 |
| MWt | 422.52 |
| Formula | C₂₅H₃₀N₂O₄ |
| Biological Activity | Iptacopan (LNP023) is a first-in-class, orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 value of 10 nM. Iptacopan shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM. Iptacopan targets the underlying cause of complement 3 glomerulopathy (C3G)[1][2]. |
| Purity | 98.66% |