TRPC6-PAM-C20
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-136190 |
| CAS # | 667427-75-0 |
| Pricing | inquire |
| Biological Activity | TRPC6-PAM-C20 is a selective positive allosteric modulator (PAM) of TRPC6 channels. TRPC6-PAM-C20 is a potent enhancer of channel activation, enabling low basal concentrations of DAG to induce activation of the ion channel. TRPC6-PAM-C20 induces increases in intracellular Ca2+ concentrations ([Ca2+]i) in TRPC6-expressing HEK293 cells with an EC50 of 2.37 μM. TRPC6-PAM-C20 can be used as a valuable tool to selectively exaggerate TRPC6-dependent signals[1]. |
| MWt | 363.41 |
| Formula | C₂₂H₂₁NO₄ |