Human 26S Proteasome Non-ATPase Regulatory Subunit 12 (PSMD12) ELISA Kit

Human 26S Proteasome Non-ATPase Regulatory Subunit 12 (PSMD12) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human 26S Proteasome Non-ATPase Regulatory Subunit 12 (PSMD12) concentrations in serum, plasma and other biological fluids. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Supplier: Abbexa Ltd.
• Product #: abx382525-96T
• Tested Applications: ELISA
• Test Range: 0.156 ng/ml - 10 ng/ml
• UniProt Primary AC: O00232
• Availability: Shipped within 5-12 working days.
• Dry Ice: No
• Note:
  • This product is for research use only.
  • The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.
  • Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.